Spectral unmixing that just works — no manual compensation.
Resolve adaptively unmixes spectral cytometry data, adjusting to variable autofluorescence and spectra across cells. Cleaner data, better marker resolution, and no more re-unmixing — all in the cloud.
Resolve
SPREADINGNEGATIVEINTENSITIESTILTED
POPULATIONSConventional
Unmixing
Your data is only as good as its unmixing.
Current tools force a tradeoff between quality and time — so teams pay for both.
Constant re-unmixing
Variable autofluorescence and spectral overlap mean the same files get unmixed again and again.
Artifacts & negative values
Fixed compensation leaves negative fluorescence and smeared populations that obscure real biology.
Hours lost to controls
Regenerating controls and hand-tuning compensation is time not spent on the science.
Adaptive unmixing, in the cloud.
Instead of one fixed compensation matrix, Resolve adapts to the autofluorescence and spectra present across different cells — so you get clean, high-quality data on the first pass.
Adapts per cell
Accounts for variable autofluorescence and spectral signatures across the sample, not a single global correction.
Eliminates negative fluorescence
Removes the negative-value artifacts that fixed compensation leaves behind.
Better marker resolution
Cleaner separation between populations means more of your panel is actually usable.
No manual compensation
Skip the controls-and-matrix grind entirely. Whether discovery or clinical, move forward with confidence.
Three steps, no local setup, no code.
Upload
Send your spectral data to the cloud — nothing to install or configure locally.
Unmix
Resolve unmixes adaptively, accounting for per-cell autofluorescence and per-cell spectral variation.
Review & export
Verify the quality, then analyze directly in the platform, or export clean, high-resolution data, ready for downstream analysis.
Pay for what you process — start free.
Buy a license and pay as you go. You're only charged for the files you run, so cost tracks usage. We onboard and train your team so you can drive it yourself.
How pricing works
Two simple components, no surprises.
★ Start with a free file allowanceWhat does unmixing really cost you?
Most files unmix cleanly. It's the fraction that don't — new single-stain controls, manual compensation, extra time on the instrument — that quietly drive the cost.
The foundation of the platform.
Resolve is tier one. When you're ready to automate biomarker endpoints for a trial, Endpoints builds directly on it — and Discovery adds unbiased annotation on top of both. Each tier includes everything below.
Discovery
Every cell population, annotated
Endpoints
Automated trial biomarker analysis
Resolve
Adaptive spectral unmixing
Run Resolve on your own data, free.
No call required. See the difference on your own spectral files.