Join our team.

Principal Software Engineer, Platform

Location: U.S. Remote (North American Time Zones) Department: Engineering

About Us

Each year people are diagnosed with cancer, autoimmune diseases, chronic conditions, and more. The immune system is the ultimate determinant of health and disease; however, current technologies used to measure the immune system are dated, fragmented, and lack the resolution, precision, and accuracy necessary to understand the interplay between our immune state and human health. Leveraging our AI-first technology, we are providing the next generation of immune profiling technology in order to fully unlock its power and accelerate drug development. And with your help, we can do it.

From technology built and proven at Fred Hutch, Ozette is creating a revolutionary immune profiling platform to turn high-dimensional data into actionable insights. Our software platform is integral to our mission – increasing data quality, measurement accuracy, accelerating drug development, and ultimately enhancing insights to drive breakthroughs and better patient outcomes.

Our founders are leading experts in data science, computational biology, and medicine and we are backed by some of the best technology investors, including Madrona Venture Group (first investors in Amazon), Microsoft co-founder Paul Allen’s Institute for Artificial Intelligence, and Vulcan Capital. If you’re passionate about leveraging technology to improve health, explore joining our innovative, creative team. Recognizing that the best candidates do not always match all criteria of the job description, we encourage you to apply if you think you would be a good fit for the role and are inspired by our mission.

This is a full time role that can be held remotely in the United States.

What you’ll do at Ozette

Own business-critical verticals, being responsible for defining and driving technical vision and roadmap, metrics, and long term iteration and maintenance.
Partner with computational biologists and researchers to architect and deliver highly parallelized scientific computing methods.
Collaborate with cross-functional teams (such as frontend engineers, data scientists, product managers) to understand requirements and design scalable and efficient solutions.
Lead cross-functional architectural initiatives spanning different layers of the backend, whether it be evolving the data model, to redesigning our async task system.
Establish engineering standards and best practices across teams
Act as a technical decision-maker for ambiguous, high-impact problems
Optimize platform performance, scalability, and reliability through efficient coding practices and infrastructure improvements
Develop with highest standards for security and compliance to ensure strict scientific integrity, reproducibility, safety, and auditability.
Perform code reviews and technical design reviews, providing constructive feedback to maintain code quality standards
Troubleshoot and resolve issues in the production environment, ensuring timely resolution of critical incidents
Communicate and document feature technical designs
Follow software development lifecycle processes
Help grow the Ozette team by both interviewing candidates and mentoring new hires

We’d love to hear from you if you have:

BS degree in Computer Science, Engineering or a related technical field, or equivalent experience
Proven experience (8+ years) as a backend software engineer on cloud-based platforms designing and developing RESTful APIs and leveraging micro services
Experience owning entire critical areas where you defined the vision, roadmap, and success.
Demonstrated fluency with Python, Typescript/Javascript, C++, Rust, and/or Go
Experience with async tasks and data pipeline technologies (e.g. Celery, K8s, and Airflow)
Proficiency in working with backend frameworks (e.g. Flask)
Strong experience in working with relational databases (e.g. PostgreSQL) and data modeling at scale
Experience with best practices in software development, including version control (tools such as GitHub), performing code reviews, and testing methodologies
Familiarity with cloud services (e.g. AWS, Azure) Experience with feature flagging, reproducibility, and versioning
Understanding of web application security principles and common vulnerabilities.
Strong interpersonal and communication skills to collaborate effectively with cross functional teams and stakeholders
Strong problem-solving and analytical skills, with the ability to debug and resolve complex technical issues.
An inclusive and entrepreneurial mindset: be a creative thinker, get things done, take failure in stride, derive signal from ambiguity, and be a champion for the team
An interest in learning biological sciences and digging into new challenges

Why You’ll Love Working Here

Ozette is dedicated to building a world-class science and technology team known for its products and services, high standards, employee development and retention. At the heart of great companies are great teams. We strive to give you everything you need to thrive at work and beyond. We offer full benefits, full-time remote work, honor all 11 federal holidays, plan company wide respites during Thanksgiving, Xmas and New Years, and offer a ‘take what you need’ vacation policy.

As an early stage employee you will get the chance to set standards and mental models that set foundations for the future, be they product, culture, or operations related. Exercise your skills across a wide gamut of responsibilities and evolve your role as the company evolves. You will
work on some of the most exciting initiatives that bridge AI/ML with hard science, packaged with a brilliant user experience.

Our work and teams thrive most when we are diverse and inclusive, so we take equal opportunity seriously. We commit to fostering a respectful, diverse, and inclusive environment where all team members can contribute and develop to their fullest potential. We welcome individuals of all backgrounds, orientations, and identities to join our community.

Compensation Range: USD $170-210k + equity